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50 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28324649 99 Sulfonamides as Selective NaEBI Amgen
28287723 73 Sulfonamides as Selective NaEBI Amgen
27994738 50 Sulfonamides as Selective NaEBI Amgen
26985315 49 Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.EBI Xenon Pharmaceuticals
25927480 36 Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications.EBI Merck Research Laboratories
24601592 48 Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis.EBI University College London
23121096 86 Ion channels as therapeutic targets: a drug discovery perspective.EBI Pfizer
22981330 7 Inhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry.EBI Universit£
21962108 14 Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA.EBI Monash University
19341281 32 Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones.EBI University College London
32392056 108 Discovery of DS-1971a, a Potent, Selective NaEBI Daiichi Sankyo
27441383 117 Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.EBI Amgen
30943032 31 Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide NaEBI Genentech
30538065 48 The discovery and optimization of benzimidazoles as selective NaEBI Pfizer
31012583 128 Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform NaEBI Siteone Therapeutics
27015369 78 Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain.EBI Abbvie
29737846 70 Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaEBI Xenon Pharmaceuticals
28988749 7 Peptide therapeutics from venom: Current status and potential.EBI Peptides International
29439904 91 Discovery of morpholine-based aryl sulfonamides as NaEBI Bristol-Myers Squibb Research and Development
29029933 45 Highly potent and selective NaEBI Pfizer
30346167 71 Discovery of Tarantula Venom-Derived NaEBI Amgen
28682065 133 Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaEBI Icagen