The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28324649 |
99 |
Sulfonamides as Selective Na |
Amgen |
28287723 |
73 |
Sulfonamides as Selective Na |
Amgen |
27994738 |
50 |
Sulfonamides as Selective Na |
Amgen |
26985315 |
49 |
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models. |
Xenon Pharmaceuticals |
25927480 |
36 |
Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications. |
Merck Research Laboratories |
24601592 |
48 |
Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis. |
University College London |
23121096 |
86 |
Ion channels as therapeutic targets: a drug discovery perspective. |
Pfizer |
22981330 |
7 |
Inhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry. |
Universit£ |
21962108 |
14 |
Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA. |
Monash University |
19341281 |
32 |
Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones. |
University College London |
32392056 |
108 |
Discovery of DS-1971a, a Potent, Selective Na |
Daiichi Sankyo |
27441383 |
117 |
Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors. |
Amgen |
30943032 |
31 |
Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na |
Genentech |
30538065 |
48 |
The discovery and optimization of benzimidazoles as selective Na |
Pfizer |
31012583 |
128 |
Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na |
Siteone Therapeutics |
27015369 |
78 |
Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain. |
Abbvie |
29737846 |
70 |
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa |
Xenon Pharmaceuticals |
28988749 |
7 |
Peptide therapeutics from venom: Current status and potential. |
Peptides International |
29439904 |
91 |
Discovery of morpholine-based aryl sulfonamides as Na |
Bristol-Myers Squibb Research and Development |
29029933 |
45 |
Highly potent and selective Na |
Pfizer |
30346167 |
71 |
Discovery of Tarantula Venom-Derived Na |
Amgen |
28682065 |
133 |
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of Na |
Icagen |